The biggest problem you may have with waiting is the possibility of the glands becoming abscessed. If that happens, you'll have to deal with treating the abscess as well as oral antibiotics. If you don't want to go with a vet visit, a groomer can also express the anal glands. It's pretty uncomfortable for them, so I wouldn't wait a REAL long time. If you have an appointment coming up in a couple of weeks, that should be fine. If it gets worse, or if he stops using the litter box, take him in immediately.
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Lori McLaughlin
Your veterinarian should ALWAYS be consulted first and foremost when your pet's welfare is at stake.