Early renal failure could still be a concern as changes in them doesn't show in bloodwork until they are over 75% damaged. He may also be having trouble tolerating the antibiotic and you may have to consider switching to a different type. If he hasn't had a urinalysis done I would consider it as this may detect damage to the kidneys that the bloodwork has not like increased protein or a low specific gravity. The Kidneys primary function is to remove toxins from the blood stream when they start malfunctioning as a result of infection, defective filtering mechanism, or neoplasia they begin to expel these toxins and lower concentration at a larger volume. . The symptoms are decreased appetite, vomiting, increased urination and increased thirst.
If he was actually diagnosed with an underactive thyroid or hypothryoidism it could be the result of an underlying illness called sick euthyroid. Most cats have the reverse condition called hyperthyroidism where the have increased weight loss dispite eating, vomiting, decreased muscle mass, and poor coat quality. Neurological symptoms can develop as well as changes in the liver values.
At this point your most important job is to try and get him to eat. Try anything. Boiled chicken, boiled hamburger, deli meat from your grocer, tuna, other canned foods should be offered. Different types of dry foods if he isn't interested in the moist. If he is eating nothing at all his liver could begin to deteriorate created a secondary issue called hepatic lipidosis or fatty liver disease. This occurs in starvation because the liver begins to metabolize fat cells. This condition is fatal without treatment.
You may need to force feed him if he is taking nothing in or too little. Water down canned food until it is gruel and use a syringe to feed him by mouth he should get 20cc of food each time. Your boy might need sub cutaneous fluids to keep up his hydration status while not eating.
He needs a recheck tomorrow at your veterinarian. You might want to request a change in antibiotic and a urinalyisis. If you suspect he hasn't eaten enough over the last 48 hours a quick check on the liver enzymes would really be a good idea. If you are noticing a yellowish color to his ears, whites of his eyes, or around his gums I would take him into the emergency center today.
Thank you
Theresa
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