Infections and diseases can cause the low white blood cell count. Distemper is one of the causes.
Distemper causes severe damage to the lining of the stomach and intestines. There are also other diseases as of the Feline Leukemia Virus. There are no specific set of symptoms that tell us for certainty that a cat has FeLV. Cats that have this virus will commonly have fevers, poor appetites, are lethargic, suffer from recurring infections, and will have experienced weight loss.
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