i have two cats they are brother and sister, even though i tried

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i have two cats they are brother and sister, even though i tried he still got her pregnant before we neutered him

Optional Information:
Age: <1; Female; Breed: siamese, persian, manx

Already Tried:
not to let her get knocked up

Customer (name blocked for privacy)

Status: Closed Value: $15

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what are the possible defects that may occur in sibling breeding